1. So Ronery – No shoulder to cry, talking to yourself way too much!

2. You can not validate ideas and implementations. No one is there to tell you that you are wrong.

3. Have to do all the work which reduces the pace of growth of the startup and increases tension, pressure and worries (many of them are unnecessary)

4. You have to pay all the expenses from your own pocket.

5. You will lose lot of Hair!

PS:Copied from Pushkar website. I have same feeling so iam sharing these article.